What medicines should not be eaten with grapefruit?

Despite all the useful properties that are contained in grapefruit, it is not recommended to use it with medicines. The fact is that the components of citrus affect the effect of medicines, significantly weakening the effect. Also, the simultaneous use of grapefruit and drugs can cause an acute negative reaction of the body.

Why is grapefruit incompatible with certain medicines?

It is proved that grapefruit, like many citrus fruits, benefits the body. Even the taste of grapefruit is unusual and tart because of the large amount of vitamins and antioxidants contained in it. The use of citrus leads to the strengthening of immunity, as well as the prevention of many diseases. Juice is used in many diets.

The reasons for the poor compatibility of the fetus with medications are as follows:

1. The content of furanocoumarins in it. These are special substances whose concentration in grapefruit is quite high. They are able to slow down the effect of the drug, affecting the action of the enzyme in the body. This enzyme is a catalyst for xenobiotic metabolism, and due to its action, the effect of the drug usually occurs instantly. In the case of the use of a medication with grapefruit, the transformation of the drug in the liver slows down, which leads to toxicity of the body.
2. The content of flavonoids in citrus, which also impede the process of catalysis of metabolism.
3. The content in it has not yet been studied substance, which inhibits the work of one of the glycoproteins. This glycoprotein is responsible for the withdrawal from the cells of the residual concentration of drugs. If this does not happen, then a large amount of toxins will accumulate in the cells.

Thus, taking the drug in parallel with grapefruit in all its forms negatively affects the body.

What drugs are not compatible with grapefruit?

Fortunately, not all drugs are poorly compatible with grapefruit. Among those that can not be taken in parallel with citrus, one can note:

1. Tranquilizers. These drugs include phenazepam, diazepam and many others. Their simultaneous administration with citrus will lead to a number of side effects - anxiety, impaired coordination, poor sleep.
2. Drugs against epilepsy. These include Carbamazepine, Lamotrigine. The combined use of these drugs together with the fruit causes a rash on the upper layer of the epithelium, as well as headaches, nausea and sleep problems.
3. Means aimed at improving blood vessels and the general condition of the blood. The common name for these medicines is sateen. This group includes drugs Lipitor, Mevacor, Zokor. Under the influence of the components contained in grapefruit, there is an increased manifestation of side effects that are present in these drugs. So, for example, severe muscle pain occurs.

Also, grapefruit is not compatible with:

• drugs that improve erectile function;
• medicines aimed at combating gastrointestinal problems;
• with immunosuppressants.

Basically, citrus reduces the effect of drugs or enhances the manifestation of side effects, which is not the best way affects the state of the body.

Reception of grapefruit along with antibiotics, as well as hormonal drugs is highly not recommended due to the fact that an intoxication process begins in the body.

If you really want a grapefruit, then what should I do?

In fact, with proper use of grapefruit, its negative effect on drugs can be avoided.

In order not to cause a negative reaction of the body, you just need to lower the amount of citrus consumed. So, for example, it is better to stretch the intake of one fetus for 2-3 days. It is also worth considering that it is advisable to eat grapefruit several hours before taking the tablets, and in no case should you drink the medicine with grapefruit juice.

Most doctors advise avoiding co-administration of grapefruit and medications, and also recommend not using lime or marmalade based on any citrus fruit.

As a conclusion, it is worth noting the fact that the use of citrus outside therapy should also be correct. Citrus should not be eaten on an empty stomach, so as not to cause irritation of the mucosa. It is also not recommended to eat fruit at night, as the action of citrus makes the liver work with increased stress, which means that during sleep the body will not be able to rest normally.

Video: why not eat grapefruit?